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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) : ASCP-MLT

ASCP-MLT

Exam Code: ASCP-MLT

Exam Name: MEDICAL LABORATORY TECHNICIAN - MLT(ASCP)

Updated: Jun 21, 2026

Q&A Number: 562 Q&As

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About ASCP ASCP-MLT Exam Questions and Answers

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ASCP-MLT Online Test Engine

ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. A patient has a WBC count of 4,000/mm3, a platelet estimation with 3 bizarre platelets/oil immersion field, hemoglobin, hematocrit, red cell count and indice values are within normal limits. Blue-staining inclusions are seen in the cytoplasm of many neutrophils. These inclusions fit the description of:

A) Dohle bodies
B) Auer rods
C) May-Hegglin bodies
D) Barr bodies


2. Immunoassay is the most common technique that is used by clinical laboratories for therapeutic drug monitoring.
Most of the drugs commonly assessed with TDM can be measured on analytical platforms which utilize antibodies (in some form) for detection. Antibodies can be developed that recognize drugs. Although most drugs are much too small to evoke an immune response, scientists can conjugate drugs to immunogenic proteins to produce antibodies that recognize drug-specific epitopes.
Which of the following is the most common technique that is used by clinical laboratories for therapeutic drug monitoring?

A) Atomic absorption
B) Electrophoresis
C) Immunoassay
D) Ion selective electrode voltimetry


3. If all newborns were tested, many positive DATs due to ABO incompatibility would be detected that are of no clinical significance.
Although many laboratories test infants born to group O Rh positive females due to the higher risk of ABO HDFN when the mother is group O, testing such infants is optional provided there is appropriate monitoring and follow-up for hyperbilirubinemia.
Blood Bank
Not performing direct antiglobulin tests (DATs) on newborns born to group O Rh positive mothers is acceptable good practice, providing there is appropriate surveillance and follow-up to detect hyperbilirubinemia.

A) true
B) false


4. Neutrophils reside in the peripheral circulation for only 7-8 hours ( approx. 7.5 hours) before entering the tissues and body cavities. This process is called diapedesis.
Hematology
How long are healthy neutrophils expected to reside in the peripheral blood of an adult?

A) 1 day
B) 3 days
C) 7-8 hours
D) 12-14 hours


5. If Kappa or Lambda is predominant and CD5 is co-expressed with CD19 (CD19/CD5 dual positive lymphocyte population), and CD23 is expressed, chronic lymphocytic leukemia is a probable diagnosis. CD19 is normally found on normal B cell populations and CD5 is normally found on mature T cell populations.
However, CD5 is present on B cells in B-chronic lymphocytic leukemia or Mantle Cell Lymphoma, both abnormal B cell malignant processes.
CD23 expression is not consistent with Mantel cells as shown on the decision tree on the right.
A monoclonal B-cell population (Kappa or Lambda predominant) with expression of CD19, CD20, CD23, and co-expression of CD5 is consistent with which of the following?

A) Mantle cell lymphoma
B) Chronic lymphocytic leukemia
C) A normal B cell
D) A mature T cell


Solutions:

Question # 1
Answer: C
Question # 2
Answer: C
Question # 3
Answer: A
Question # 4
Answer: C
Question # 5
Answer: B

Related Certifications
MLT(ASCP)
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